Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883541 | 0.82 | ALDH1A1 (0.42) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL17691229 | 0.79 | PNMT (0.44) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL199109 | 0.77 | HDAC4 (0.53) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL26239181 | 0.77 | HDAC4 (0.53) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL13158651 | 0.77 | ALDH1A1 (0.46) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL25819608 | 0.77 | HDAC4 (0.53) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL15842196 | 0.77 | ALDH1A1 (0.46) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL15866411 | 0.77 | ALDH1A1 (0.46) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL25392233 | 0.77 | TAAR1 (0.52) | AOC3ALDH1A1 | |
| SCHEMBL16204365 | 0.76 | TAAR1 (0.57) | PNMTAOC3ALDH1A1HPGDPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158464-A1 | REVERSE AMIDE-LINKED MELANOCORTIN RECEPTOR-SPECIFIC CYCLIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |