Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26239181 | 1.00 | HDAC4 (0.53) | HDAC4HDAC2HDAC8PNMTAOC3 | |
| SCHEMBL199109 | 1.00 | HDAC4 (0.53) | HDAC4HDAC2HDAC8PNMTAOC3 | |
| SCHEMBL16629816 | 0.89 | HDAC4 (0.47) | HDAC4HDAC2HDAC8PNMTALDH1A1 | |
| SCHEMBL1006801 | 0.84 | HDAC4 (0.62) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL18923583 | 0.84 | OPRM1 (0.44) | HDAC4HDAC2HDAC8PNMTAOC3 | |
| SCHEMBL13158651 | 0.83 | ALDH1A1 (0.46) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL15842196 | 0.83 | ALDH1A1 (0.46) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL15866411 | 0.83 | ALDH1A1 (0.46) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL16204375 | 0.82 | TAAR1 (0.57) | PNMTAOC3ALDH1A1HPGDPGR | |
| SCHEMBL17691229 | 0.82 | PNMT (0.44) | PNMTAOC3ALDH1A1HPGDPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212523-A1 | PYRAZOLE AMIDE COMPOUNDS AS IRAK INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |