Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSLP | Q969D9 | 2/20 | 0.44 |
| ▸ | MC4R | P32245 | 10/20 | 0.42 |
| ▸ | MC1R | Q01726 | 10/20 | 0.42 |
| ▸ | MC5R | P33032 | 9/20 | 0.42 |
| ▸ | MC3R | P41968 | 9/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24991154 | 0.93 | TSLP (0.44) | TSLPMC4RMC1RMC5RMC3R | |
| SCHEMBL24990017 | 0.93 | TSLP (0.44) | TSLPMC4RMC1RMC5RMC3R | |
| SCHEMBL23745173 | 0.92 | MC4R (0.47) | TSLPMC4RMC1RMC5RMC3R | |
| SCHEMBL23750043 | 0.91 | TSLP (0.45) | TSLPMC4RMC1RMC5RMC3R | |
| SCHEMBL24991116 | 0.90 | TSLP (0.44) | TSLPMC4RMC1RMC5RMC3R | |
| SCHEMBL24991502 | 0.86 | FURIN (0.44) | TSLPMC4RMC1RMC5RMC3R | |
| SCHEMBL24991019 | 0.84 | TSLP (0.48) | TSLPMC4RFURINCTSDPLG | |
| SCHEMBL23750032 | 0.84 | MC4R (0.50) | TSLPMC4RMC1RMC5RMC3R | |
| SCHEMBL24991137 | 0.84 | TSLP (0.43) | TSLPMC4RMC1RMC5RMC3R | |
| SCHEMBL20206353 | 0.83 | TSLP (0.49) | TSLPMC4RMC1RFURINACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158464-A1 | REVERSE AMIDE-LINKED MELANOCORTIN RECEPTOR-SPECIFIC CYCLIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |