Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 12/20 | 0.47 |
| ▸ | MC5R | P33032 | 12/20 | 0.47 |
| ▸ | MC3R | P41968 | 12/20 | 0.47 |
| ▸ | MC1R | Q01726 | 11/20 | 0.47 |
| ▸ | TSLP | Q969D9 | 5/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745174 | 0.92 | TSLP (0.44) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL23750043 | 0.89 | TSLP (0.45) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL24991116 | 0.88 | TSLP (0.44) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL24991154 | 0.87 | TSLP (0.44) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL24990017 | 0.87 | TSLP (0.44) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL20206353 | 0.81 | TSLP (0.49) | MC4RMC1RTSLPACEACE2 | |
| SCHEMBL24991137 | 0.81 | TSLP (0.43) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL24991502 | 0.80 | FURIN (0.44) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL24991019 | 0.78 | TSLP (0.48) | MC4RTSLPPLG | |
| SCHEMBL24990207 | 0.77 | TSLP (0.44) | MC4RMC5RMC3RMC1RTSLP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158464-A1 | REVERSE AMIDE-LINKED MELANOCORTIN RECEPTOR-SPECIFIC CYCLIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |