Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563428 | 1.00 | DDB1 (0.51) | DDB1CRBNALDH1A1KMT2ARAB9A | |
| SCHEMBL20805394 | 0.78 | ALDH1A1 (0.56) | DDB1CRBNALDH1A1KMT2ARAB9A | |
| SCHEMBL19510001 | 0.77 | DDB1 (0.43) | DDB1CRBNALDH1A1KMT2ARAB9A | |
| SCHEMBL14467184 | 0.76 | KDM4E (0.49) | DDB1CRBNALDH1A1RAB9AMAPT | |
| SCHEMBL14467140 | 0.75 | TDP1 (0.40) | DDB1CRBNALDH1A1RAB9AMAPT | |
| SCHEMBL14466142 | 0.74 | NPC1 (0.38) | DDB1CRBNALDH1A1RAB9AMAPT | |
| SCHEMBL9822927 | 0.73 | MAPT (0.46) | ALDH1A1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL10242830 | 0.71 | ALDH1A1 (0.44) | DDB1CRBNALDH1A1KMT2ARAB9A | |
| SCHEMBL13363233 | 0.71 | TDP1 (0.40) | ALDH1A1MAPTTSHRTDP1GSK3B | |
| SCHEMBL395878 | 0.71 | TDP1 (0.66) | DDB1CRBNALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |