Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 4/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 8/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23727306 | 0.80 | ADAMTS5 (0.53) | MMP13MMP2ADAMTS5ADAMTS4ADAM17 | |
| SCHEMBL29835150 | 0.80 | ADAMTS5 (0.53) | MMP13MMP2ADAMTS5ADAMTS4ADAM17 | |
| SCHEMBL23727305 | 0.80 | ADAMTS5 (0.53) | MMP13MMP2ADAMTS5ADAMTS4ADAM17 | |
| SCHEMBL23745322 | 0.74 | DPP7 (0.40) | MMP13MMP12MMP14MMP2ADAMTS5 | |
| SCHEMBL30013223 | 0.72 | ABHD6 (0.38) | BACE1ESR1ESR2MGLLABHD6 | |
| SCHEMBL23745358 | 0.67 | ADAMTS4 (0.67) | MMP13MMP12MMP2ADAMTS5ADAMTS4 | |
| SCHEMBL29250257 | 0.66 | ADAMTS5 (0.55) | MMP13MMP2ADAMTS5ADAMTS4ADAM17 | |
| SCHEMBL29835134 | 0.66 | ADAMTS5 (0.55) | MMP13MMP2ADAMTS5ADAMTS4ADAM17 | |
| SCHEMBL23745214 | 0.66 | ADAMTS5 (0.55) | MMP13MMP2ADAMTS5ADAMTS4ADAM17 | |
| SCHEMBL23745243 | 0.65 | ADAMTS5 (0.54) | MMP13MMP14MMP2ADAMTS5ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |