Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.57 |
| ▸ | ADAMTS5 | Q9UNA0 | 19/20 | 0.57 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745413 | 0.87 | ADAMTS5 (0.69) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 | |
| SCHEMBL31121194 | 0.87 | ADAMTS5 (0.69) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 | |
| SCHEMBL23745410 | 0.81 | MMP2 (0.65) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 | |
| SCHEMBL29262510 | 0.80 | ADAMTS5 (0.66) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 | |
| SCHEMBL23745411 | 0.80 | ADAMTS5 (0.62) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 | |
| SCHEMBL23745396 | 0.78 | ADAMTS5 (0.72) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 | |
| SCHEMBL23727487 | 0.78 | ADAMTS5 (0.65) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 | |
| SCHEMBL23745406 | 0.78 | ADAMTS5 (0.66) | MMP2ADAMTS5ADAMTS4MMP13ADAM17 | |
| SCHEMBL23727486 | 0.78 | ADAMTS5 (0.65) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 | |
| SCHEMBL29835187 | 0.78 | ADAMTS5 (0.65) | MMP2ADAMTS5ADAMTS4MMP13ADAMTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |