Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745636 | 0.96 | SOS1 (0.48) | SOS1ICMTMPOCNR1MAPT | |
| Hydrochloric Acid SCHEMBL23722065 | 0.95 | SOS1 (0.47) | SOS1ICMTMPOSLC6A4CNR1 | |
| SCHEMBL23745598 | 0.94 | SOS1 (0.44) | SOS1HTR4CNR1 | |
| SCHEMBL23745812 | 0.94 | SOS1 (0.42) | SOS1ICMTMPOSLC6A4HDAC1 | |
| Hydrochloric Acid SCHEMBL23721995 | 0.93 | SOS1 (0.41) | SOS1ICMTMPOSLC6A4HDAC1 | |
| Hydrochloric Acid SCHEMBL23722114 | 0.93 | SOS1 (0.44) | SOS1HTR4CNR1 | |
| SCHEMBL23745733 | 0.89 | CNR1 (0.41) | SOS1ICMTMPOCNR1MAPT | |
| Hydrochloric Acid SCHEMBL23722160 | 0.88 | CNR1 (0.40) | SOS1ICMTMPOCNR1MAPT | |
| SCHEMBL23722038 | 0.88 | SOS1 (0.41) | SOS1ICMTCNR1 | |
| SCHEMBL23745874 | 0.86 | ICMT (0.34) | SOS1ICMTSLC6A4HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | FDPS, FPR1, F12 | SOS1 2902/4885ICMT 345/4885MPO 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.