SCHEMBL23745580

SCHEMBL23745580

Cc1cccc(C(CCNC2CCNCC2)c2cn(C3CCNCC3)c3ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 3/20 0.50
HTR6 P50406 5/20 0.39
PRKCG P05129 1/20 0.37
PRKCB P05771 1/20 0.37
PRKCA P17252 1/20 0.37
PRKCH P24723 1/20 0.37
PRKCE Q02156 1/20 0.37
PRKCZ Q05513 1/20 0.37
PRKCD Q05655 1/20 0.37
CAMK2B Q13554 1/20 0.37
CAMK2G Q13555 1/20 0.37
CAMK2D Q13557 1/20 0.37
CAMK2A Q9UQM7 1/20 0.37
MPO P05164 3/20 0.33
HTR4 Q13639 1/20 0.33
ACHE P22303 1/20 0.32
BACE1 P56817 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23721946 0.99 SOS1 (0.49) SOS1HTR6PRKCGPRKCBPRKCA
SCHEMBL23745826 0.96 SOS1 (0.51) SOS1HTR6PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL23722094 0.95 SOS1 (0.50) SOS1HTR6PRKCGPRKCBPRKCA
SCHEMBL23745456 0.95 SOS1 (0.50) SOS1HTR6PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL23722150 0.95 SOS1 (0.49) SOS1HTR6PRKCGPRKCBPRKCA
SCHEMBL23722039 0.94 SOS1 (0.43) SOS1HTR6PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL23721969 0.93 SOS1 (0.43) SOS1HTR6PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL23722073 0.93 SOS1 (0.43) SOS1HTR6PRKCGPRKCBPRKCA
SCHEMBL23745749 0.86 SOS1 (0.44) SOS1MPOACHEBACE1
SCHEMBL23745514 0.85 SOS1 (0.48) SOS1MPOHTR4ACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246115-A1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF BIOIMICS AB (SE) 2021-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246115-A1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF FDPS, FPR1, F12 SOS1 2902/4885HTR6 4724/4885PRKCG 4528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.