Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23722189 | 0.99 | CNR1 (0.38) | CNR1PADI4PDE4APDE4BPDE4C | |
| SCHEMBL23745835 | 0.86 | KDM4E (0.35) | MPOAKT1ROCK2MAP4K4PRKCG | |
| Hydrochloric Acid SCHEMBL23722121 | 0.85 | KDM4E (0.35) | MPOAKT1ROCK2MAP4K4PRKCG | |
| SCHEMBL23745823 | 0.84 | CNR1 (0.38) | CNR1PADI4PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL23722097 | 0.84 | CNR1 (0.38) | CNR1PADI4PDE4APDE4BPDE4C | |
| SCHEMBL23745599 | 0.84 | MPO (0.43) | CNR1PADI4PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL23722095 | 0.83 | MPO (0.42) | CNR1PADI4PDE4APDE4BPDE4C | |
| SCHEMBL23745569 | 0.82 | SOS1 (0.48) | CNR1PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL23722157 | 0.81 | SOS1 (0.47) | CNR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23745689 | 0.76 | KDM4E (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | FDPS, FPR1, F12 | CNR1 1651/4885PADI4 1142/4885PDE4A 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.