SCHEMBL23745808

SCHEMBL23745808

Cc1cccc(C(CC(=O)NC2CCC(N)CC2)c2cn(CC3CCCCC3)c3ccc(-c4ccccc4Cl)cc23)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ICMT O60725 7/20 0.41
GRIN2B Q13224 1/20 0.36
KMT2A Q03164 2/20 0.35
CNR1 P21554 1/20 0.35
MAPT P10636 1/20 0.35
CCR1 P32246 1/20 0.34
KRAS P01116 1/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
RAB9A P51151 1/20 0.34
TP53 P04637 1/20 0.34
CNR2 P34972 2/20 0.34
NPY5R Q15761 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23745806 1.00 ICMT (0.41) ICMTGRIN2BKMT2ACNR1MAPT
Hydrochloric Acid SCHEMBL23721889 0.99 ICMT (0.41) ICMTGRIN2BKMT2ACNR1MAPT
SCHEMBL23745854 0.93 ICMT (0.42) ICMTGRIN2BKMT2ACNR1MAPT
SCHEMBL23745855 0.93 ICMT (0.42) ICMTGRIN2BKMT2ACNR1MAPT
SCHEMBL23722107 0.92 ICMT (0.48) ICMTGRIN2BKMT2ACNR1CCR1
SCHEMBL23745742 0.92 ICMT (0.48) ICMTGRIN2BKMT2ACNR1CCR1
SCHEMBL23745578 0.91 ICMT (0.49) ICMTKMT2AKRAS
Hydrochloric Acid SCHEMBL23721849 0.91 ICMT (0.47) ICMTGRIN2BKMT2ACNR1CCR1
Hydrochloric Acid SCHEMBL23722012 0.89 ICMT (0.41) ICMTKMT2ACNR1CCR1KRAS
SCHEMBL23745594 0.88 CNR1 (0.42) ICMTKMT2ACNR1MAPTCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246115-A1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF BIOIMICS AB (SE) 2021-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246115-A1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF FDPS, FPR1, F12 ICMT 345/4885GRIN2B 4667/4885KMT2A 4684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.