Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747030 | 0.84 | FKBP1A (0.43) | FKBP1ACHRNA7HTR3AGLAKMT2A | |
| SCHEMBL23746997 | 0.78 | EGFR (0.43) | EGFRKDRCHRNA7HTR3AALDH1A1 | |
| SCHEMBL23746999 | 0.77 | EGFR (0.42) | EGFRKDRCHRNA7HTR3AALDH1A1 | |
| SCHEMBL23746994 | 0.76 | EGFR (0.45) | EGFRKDRALDH1A1LMNAHPGD | |
| SCHEMBL23746986 | 0.75 | EGFR (0.44) | EGFRKDRCHRNA7HTR3AALDH1A1 | |
| SCHEMBL23747097 | 0.72 | KDM4E (0.47) | EGFRKDRKMT2AALDH1A1HPGD | |
| SCHEMBL19864853 | 0.72 | EGFR (0.55) | EGFRKDRCHRNA7HTR3AGLA | |
| SCHEMBL23747000 | 0.71 | EGFR (0.47) | EGFRKDRKMT2AALDH1A1KDM4E | |
| SCHEMBL23746992 | 0.71 | EGFR (0.42) | EGFRKDRCHRNA7HTR3A | |
| SCHEMBL23747019 | 0.71 | EGFR (0.47) | EGFRKDRKMT2ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158516-A1 | IRE1α MODULATORS AND USES THEREOF | NIMBUS IASO, INC. (US) | 2021-08-12 | — | — | WO | disclosed |