SCHEMBL23747012

SCHEMBL23747012

CCCCn1cc(CCN(C)C)c2c(OP(=O)(O)O)cccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 8/20 1.00
HTR2A P28223 7/20 1.00
HTR2B P41595 5/20 1.00
HTR1A P08908 1/20 0.53
HTR6 P50406 6/20 0.42
DNM2 P50570 4/20 0.39
ICMT O60725 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361303 0.86 HTR2C (0.75) HTR2CHTR2AHTR2BHTR1AHTR6
SCHEMBL23723408 0.86 HTR2C (0.75) HTR2CHTR2AHTR2BHTR1AHTR6
SCHEMBL30356554 0.84 HTR2C (1.00) HTR2CHTR2AHTR2BHTR1AHTR6
SCHEMBL29405683 0.84 HTR2C (1.00) HTR2CHTR2AHTR2BHTR1AHTR6
SCHEMBL23805226 0.79 HTR2A (1.00) HTR2CHTR2AHTR2BHTR1AHTR6
SCHEMBL23805220 0.79 HTR2A (0.65) HTR2CHTR2AHTR2BHTR6DNM2
SCHEMBL23723381 0.79 HTR2A (0.65) HTR2CHTR2AHTR2BHTR1AHTR6
SCHEMBL25074655 0.77 HTR2C (0.69) HTR2CHTR2AHTR2BHTR1AHTR6
SCHEMBL3176621 0.74 HTR2C (0.59) HTR2CHTR2AHTR2BHTR1AHTR6
SCHEMBL31188169 0.74 HTR2C (0.59) HTR2CHTR2AHTR2BHTR1AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS SYNAPTIVE THERAPEUTICS, LLC 2024-11-07 US disclosed
US-20230405026-A1 A Method of Treating Depression by Immune Modulation MYND LIFE SCIENCES INC (CA) 2023-12-21 US disclosed
WO-2021155467-A1 3-PYRROLIDINE-INDOLE DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS MINDSET PHARMA INC. (CA) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS HTR1B, HTR2B, PNMT HTR2C 4/4885HTR2A 5/4885HTR2B 2/4885
US-20230405026-A1 A Method of Treating Depression by Immune Modulation ABCF1, ABCF2, ABCB4 HTR2C 1196/4885HTR2A 377/4885HTR2B 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.