SCHEMBL23723381

SCHEMBL23723381

[2H]C([2H])([2H])N(CCc1cn(CP(=O)(O)O)c2cccc(OP(=O)(O)O)c12)C([2H])([2H])[2H]

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 9/20 0.65
HTR2C P28335 8/20 0.65
HTR2B P41595 5/20 0.65
HTR1A P08908 1/20 0.47
HTR6 P50406 4/20 0.38
INPPL1 O15357 1/20 0.33
INPP5B P32019 1/20 0.33
INPP5A Q14642 1/20 0.33
HDAC1 Q13547 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
PLA2G2A P14555 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361303 0.92 HTR2C (0.75) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL23723408 0.92 HTR2C (0.75) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL23723323 0.88 HTR2C (0.50) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL25662706 0.80 HTR2C (0.58) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL23747012 0.79 HTR2C (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL29405683 0.78 HTR2C (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL30356554 0.78 HTR2C (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL23723275 0.77 HTR2A (0.44) HTR2AHTR2CHTR2BHTR6HDAC1
SCHEMBL29936591 0.76 HTR2C (0.70) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL23723320 0.76 HTR2C (0.70) HTR2AHTR2CHTR2BHTR1AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118373809-A Quinoxalinone compound and preparation method, pharmaceutical composition and application thereof 徐州医科大学 2024-07-23 CN claimed
CN-109970717-B 4- (alicyclic pyrimidine/pyridine substituted) amino-1H-3-pyrazolecarboxamide FLT3 inhibitor and application thereof 中国药科大学 2022-10-18 CN claimed
EP-4747249-A1 TREM2 MODULATORS Muna Therapeutics ApS (DK) 2026-05-27 EP disclosed
CN-114401960-B Glue degradation agent and using method thereof NOVARTIS AG (CH) 2026-05-26 CN disclosed
US-20260116901-A1 PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS MINDSET PHARMA INC. (CA) 2026-04-30 US disclosed
US-20260078125-A1 TYK2 INHIBITORS AND USES THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2026-03-19 US disclosed
US-20250388611-A1 PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS MINDSET PHARMA, INC. (CA) 2025-12-25 US disclosed
EP-3612030-B1 INDOLE AHR INHIBITORS AND USES THEREOF IKENA ONCOLOGY INC (US) 2025-12-24 EP disclosed
WO-2025229624-A2 NEW CD38 INHIBITORS NAPA THERAPEUTICS LIMITED (GB) 2025-11-06 WO disclosed
US-12410183-B2 Sars-cov2 main protease inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
US-12378266-B2 Psilocin derivatives as serotonergic psychedelic agents for the treatment of CNS disorders MINDSET PHARMA INC. (CA) 2025-08-05 US disclosed
WO-2022136914-A1 TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2022-06-30 WO disclosed
US-11358969-B2 Indole AHR inhibitors and uses thereof Ikena Oncology, Inc. (US) 2022-06-14 US disclosed
CN-114605344-A Oxadiazole compound, preparation method and application 西北农林科技大学 2022-06-10 CN disclosed
EP-4006039-A1 FUSED DIHYDRO-4H-PYRAZOLO[5,1-C][1,4]OXAZINYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS Sunovion Pharmaceuticals Inc. (US) 2022-06-01 EP disclosed
CN-114401960-A Glue degradation agent and use method thereof 诺华股份有限公司 2022-04-26 CN disclosed
US-20220073528-A1 TYK2 INHIBITORS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-03-10 US disclosed
EP-3958861-A1 DEGRADERS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF Dana-Farber Cancer Institute, Inc. (US) 2022-03-02 EP disclosed
US-20220024956-A1 PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS MINDSET PHARMA INC. (CA) 2022-01-27 US disclosed
WO-2021155470-A1 PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS MINDSET PHARMA INC. (CA) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11358969-B2 Indole AHR inhibitors and uses thereof AHR, ARNT, IDO1 HTR2A 69/4885HTR2C 74/4885HTR2B 101/4885
US-20220024956-A1 PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS HTR1A, HTR6, HTR1B HTR2A 4/4885HTR2C 7/4885HTR2B 13/4885
US-12378266-B2 Psilocin derivatives as serotonergic psychedelic agents for the treatment of CNS disorders HTR1A, HTR6, HTR1B HTR2A 4/4885HTR2C 7/4885HTR2B 13/4885
US-20220073528-A1 TYK2 INHIBITORS AND USES THEREOF TYK2, JAK2, JAK1 HTR2A 3475/4885HTR2C 3262/4885HTR2B 3398/4885
US-12410183-B2 Sars-cov2 main protease inhibitors ACE2, TMPRSS2, ACE HTR2A 2757/4885HTR2C 1491/4885HTR2B 2735/4885
US-20260078125-A1 TYK2 INHIBITORS AND USES THEREOF TYK2, JAK2, JAK3 HTR2A 1403/4885HTR2C 587/4885HTR2B 954/4885
US-20250388611-A1 PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS HTR6, CNR1, HTR1D HTR2A 16/4885HTR2C 5/4885HTR2B 28/4885
US-20260116901-A1 PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS HTR6, CNR1, HTR2C HTR2A 13/4885HTR2C 3/4885HTR2B 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.