Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747090 | 0.84 | USP30 (0.39) | PRMT5TRPV1FPR3FPR2KDM1A | |
| SCHEMBL889104 | 0.83 | PRMT5 (0.46) | PRMT5TRPV1FPR3FPR2KDM1A | |
| SCHEMBL7204445 | 0.83 | PRMT5 (0.46) | PRMT5TRPV1FPR3FPR2KDM1A | |
| SCHEMBL23747113 | 0.82 | IDO1 (0.50) | FPR3FPR2KDM1ACHEK2IDO1 | |
| SCHEMBL23747243 | 0.82 | IDO1 (0.50) | FPR3FPR2KDM1ACHEK2IDO1 | |
| SCHEMBL12810228 | 0.81 | HCRTR1 (0.53) | PRMT5TRPV1FPR3FPR2CHEK2 | |
| SCHEMBL12810103 | 0.80 | FPR3 (0.49) | PRMT5TRPV1FPR3FPR2KDM1A | |
| SCHEMBL23747146 | 0.79 | USP30 (0.41) | IDO1TDO2 | |
| SCHEMBL31460749 | 0.78 | ALDH1A1 (0.44) | KDM1AIDO1TDO2GPR119 | |
| SCHEMBL1597840 | 0.77 | PRMT5 (0.44) | PRMT5TRPV1FPR3FPR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158516-A1 | IRE1α MODULATORS AND USES THEREOF | NIMBUS IASO, INC. (US) | 2021-08-12 | — | — | WO | disclosed |