SCHEMBL2374739

SCHEMBL2374739

[N]=Nc1ccccc1[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.58
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 5/20 0.46
ALDH1A1 P00352 7/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 1/20 0.45
GPR35 Q9HC97 1/20 0.45
HPGD P15428 1/20 0.44
CCNT1 O60563 1/20 0.44
CCNB2 O95067 1/20 0.44
CCNE2 O96020 1/20 0.44
CDK1 P06493 1/20 0.44
CDK4 P11802 1/20 0.44
CCNB1 P14635 1/20 0.44
CCNA2 P20248 1/20 0.44
CCND1 P24385 1/20 0.44
CCNE1 P24864 1/20 0.44
CDK2 P24941 1/20 0.44
CDK7 P50613 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10768606 0.83 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL3184824 0.82 PLAU (0.62) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL7784505 0.82 GPR35 (0.53) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL3305095 0.80 TDP1 (0.64) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL4365348 0.80 PLAU (0.60) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL30184963 0.80 PLAU (0.60) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL10798681 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL8013238 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL28331734 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL30184964 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024085073-A1 PHOTOELECTRIC CONVERSION ELEMENT キヤノン株式会社 2024-04-25 WO claimed
CN-109763184-A A kind of production method of the magnetic oxygenated graphene-carbon nano tube conductive fiber of orientationization 重庆中科烯维科技有限公司 2019-05-17 CN claimed
CN-106876601-A Organic light-emitting display device 乐金显示有限公司 2017-06-20 CN claimed
CN-103946922-B Photorefractive composite 明斯特威斯特法伦威廉大学 2017-02-22 CN claimed
US-9287568-B2 High performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-15 US claimed
CN-102519959-A Highly sensitive pH test paper and preparation method thereof SHANGHAI XINSHENGSHI CHEMICAL TECHNOLOGY CO LTD 2012-06-27 CN claimed
US-8198436-B2 Colorimetric detection of cyanide with a chromogenic oxazine THE UNIVERSITY OF MIAMI (US) 2012-06-12 US claimed
US-20110319257-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US claimed
EP-2150588-A2 POLYMERIC DYES BASED ON POLYMERIZABLE VINYL-GROUP CONTAINIG P-NITROPHENYL-AZO SALICYLIC ACID DERIVATIVES Benz Research and Development Corporation (US) 2010-02-10 EP claimed
US-20090258429-A1 Colorimetric detection of cyanide with a chromogenic oxazine MIAMI, THE UNIVERSITY OF 2009-10-15 US claimed
WO-2008134555-A2 POLYMERIC DYES BASED ON POLYMERIZABLE VINYL-GROUP CONTAINING P-NITROPHENYL-AZO SALICYLIC ACID DERIVATIVES BENZ RESEARCH AND DEVELOPMENT CORPORATION (US) 2008-11-06 WO claimed
WO-2007028080-A1 COLORIMETRIC DETECTION OF CYANIDE WITH A CHROMOGENIC OXAZINE THE UNIVERSITY OF MIAMI (US) 2007-03-08 WO claimed
US-5874432-A Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof SANOFI (FR) 1999-02-23 US claimed
US-5733481-A FLUORINATED POLYAMIC ACID AND ELECTROOPTIC PERYLENE COMPOUND HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-03-31 US claimed
US-5371074-A Use of saccharin derivatives as proteolytic enzyme inhibitors STERLING WINTHROP INC. (US) 1994-12-06 US claimed
EP-0542372-A1 2-Substituted saccharin derivative proteolytic enzyme inhibitors STERLING WINTHROP INC. (US) 1993-05-19 EP claimed
US-4439362-A DISPERSE DYES, POLYESTERS SANDOZ LTD. (CH) 1984-03-27 US claimed
US-4140684-A FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ACETATES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1979-02-20 US claimed
US-4011208-A 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES SANDOZ LTD. (CH) 1977-03-08 US claimed
US-3943120-A WATER INSOLUBLE CIBA-GEIGY AG (CH) 1976-03-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258429-A1 Colorimetric detection of cyanide with a chromogenic oxazine CBR3, CBR1, CYCS PLAU 4593/4885HSD17B10 2822/4885TDP1 960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.