SCHEMBL8013238

SCHEMBL8013238

N=Nc1ccccc1[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.58
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 5/20 0.46
ALDH1A1 P00352 6/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 1/20 0.45
GPR35 Q9HC97 1/20 0.45
CCNT1 O60563 1/20 0.44
CCNB2 O95067 1/20 0.44
CCNE2 O96020 1/20 0.44
CDK1 P06493 1/20 0.44
CDK4 P11802 1/20 0.44
CCNB1 P14635 1/20 0.44
CCNA2 P20248 1/20 0.44
CCND1 P24385 1/20 0.44
CCNE1 P24864 1/20 0.44
CDK2 P24941 1/20 0.44
CDK7 P50613 1/20 0.44
CDK9 P50750 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3184824 0.82 PLAU (0.62) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL8222001 0.80 TDP1 (0.64) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL30184963 0.80 PLAU (0.60) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL4365348 0.80 PLAU (0.60) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL10798681 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL28331734 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL30184964 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL16665353 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL10768606 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1
SCHEMBL2374739 0.78 PLAU (0.58) PLAUHSD17B10TDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10007665-A None JP disclosed
CN-117886766-A Method for synthesizing 2-aryl-2H-benzotriazole compound by driving visible light and application thereof 汕头大学 2024-04-16 CN disclosed
US-10838111-B2 Optical material comprising a red-shifted benzotriazole UV absorber ESSILOR INTERNATIONAL (FR) 2020-11-17 US disclosed
US-20190107647-A1 OPTICAL MATERIAL COMPRISING A RED-SHIFTED BENZOTRIAZOLE UV ABSORBER ESSILOR INTERNATIONAL (FR) 2019-04-11 US disclosed
EP-3236296-A1 OPTICAL MATERIAL COMPRISING A RED-SHIFTED BENZOTRIAZOLE UV ABSORBER ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) 2017-10-25 EP disclosed
CN-103351349-B Synthetic method for benzotriazole ultraviolet absorbent UV-P TIANCHANG TIANJIA CHEMICAL TECHNOLOGY CO LTD 2015-02-04 CN disclosed
CN-103351349-A Synthetic method for benzotriazole ultraviolet absorbent UV-P TIANCHANG TIANJIA CHEMICAL TECHNOLOGY CO LTD 2013-10-16 CN disclosed
EP-0594047-B1 Arylazo chromoionophores BAYER AG (US) 2000-01-05 EP disclosed
JP-H107665-A PREPARATION OF 2-(2'-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVE EASTMAN KODAK CO 1998-01-13 JP disclosed
US-5571924-A Process for the preparation of benzotriazoles CIBA-GEIGY CORPORATION (US) 1996-11-05 US disclosed
EP-0625971-A4 UV LIGHT STABILIZING, ANTIOXIDANT AND COLORANT COMPOUNDS. 1995-01-04 EP disclosed
EP-0625971-A1 UV LIGHT STABILIZING, ANTIOXIDANT AND COLORANT COMPOUNDS HOECHST CELANESE CORPORATION (US) 1994-11-30 EP disclosed
US-5310888-A Calcium detection MILES INC. (US) 1994-05-10 US disclosed
EP-0594047-A1 Arylazo chromoionophores Bayer Corporation (US) 1994-04-27 EP disclosed
US-5276161-A Catalytic hydrogenation of o-nitrophenylazohydroxyphenyl compounds; noble metal catalyst and organic amine CIBA-GEIGY CORPORATION (US) 1994-01-04 US disclosed
WO-1993015063-A1 UV LIGHT STABILIZING, ANTIOXIDANT AND COLORANT COMPOUNDS HOECHST CELANESE CORPORATION (US) 1993-08-05 WO disclosed
US-4999433-A Process for the preparation of benzotriazole derivatives CIBA-GEIGY CORPORATION (US) 1991-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190107647-A1 OPTICAL MATERIAL COMPRISING A RED-SHIFTED BENZOTRIAZOLE UV ABSORBER CRY2, ALDH1A2, CRY1 PLAU 3615/4885HSD17B10 2065/4885TDP1 1842/4885
US-10838111-B2 Optical material comprising a red-shifted benzotriazole UV absorber CRY2, ALDH1A2, CRY1 PLAU 3615/4885HSD17B10 2065/4885TDP1 1842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.