Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 5/20 | 0.55 |
| ▸ | LSS | P48449 | 1/20 | 0.55 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.53 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 4/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747313 | 0.89 | CHRM1 (0.62) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL23747684 | 0.86 | CHRM1 (0.65) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL23747730 | 0.79 | RORC (0.72) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL19570474 | 0.79 | RORC (0.72) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL23747449 | 0.78 | RAB9A (0.74) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL23727986 | 0.76 | RAB9A (0.75) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL23727642 | 0.76 | RAB9A (0.75) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL5113946 | 0.76 | MCHR1 (1.00) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL23747699 | 0.76 | RAB9A (0.70) | CHRM1HTR2AMCHR1RAB9APOLB | |
| SCHEMBL23747520 | 0.74 | RAB9A (0.73) | CHRM1HTR2AMCHR1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |