Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15544576 | 0.87 | MAPT (0.48) | MAPTL3MBTL1HTR2AHTR2CHPGD | |
| SCHEMBL23748136 | 0.82 | HTR2C (0.45) | MAPTL3MBTL1HTR2AHTR2CHPGD | |
| SCHEMBL1520406 | 0.81 | ALDH1A1 (0.47) | MAPTHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1923931 | 0.81 | ALDH1A1 (0.46) | HPGDALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL28528791 | 0.81 | ALDH1A1 (0.46) | MAPTL3MBTL1HPGDALDH1A1HTT | |
| SCHEMBL4619965 | 0.80 | HPGD (0.54) | MAPTHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3954852 | 0.80 | GAA (0.41) | MAPTHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3694739 | 0.80 | ERN1 (0.41) | MAPTL3MBTL1HPGDALDH1A1HTT | |
| SCHEMBL10158234 | 0.80 | ERN1 (0.40) | MAPTL3MBTL1HPGDALDH1A1HTT | |
| SCHEMBL2523798 | 0.80 | GAA (0.55) | MAPTL3MBTL1HPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954762-A | 3-Cyanoethyl substituted-4-chromanone compound and preparation method thereof | 湖南科技学院 | 2025-05-09 | — | — | CN | disclosed |
| CN-119350284-A | Photocatalytic synthesis method of benzodihydropyran-4-ketone compound containing trifluoromethyl | 湖南科技学院 | 2025-01-24 | — | — | CN | disclosed |
| CN-116789626-A | Preparation method of aromatic chroman-4-one compound containing amide group | 湖南科技学院 | 2023-09-22 | — | — | CN | disclosed |
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | JANSSEN BIOPHARMA INC (US) | 2023-01-05 | — | — | US | disclosed |
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | JANSSEN BIOPHARMA INC (US) | 2023-01-05 | — | — | US | disclosed |
| US-11312727-B1 | Macrocyclic flu endonuclease inhibitors | Janssen Biopharma, Inc. (US) | 2022-04-26 | — | — | US | disclosed |
| US-11312727-B1 | Macrocyclic flu endonuclease inhibitors | Janssen Biopharma, Inc. (US) | 2022-04-26 | — | — | US | disclosed |
| EP-3864020-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | Janssen BioPharma, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | ACE, PNP, FEN1 | MAPT 2999/4885L3MBTL1 2124/4885HTR2A 2921/4885 |
| US-11312727-B1 | Macrocyclic flu endonuclease inhibitors | ACE, FEN1, PNP | MAPT 3026/4885L3MBTL1 3042/4885HTR2A 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.