SCHEMBL1923931

SCHEMBL1923931

C=CCOc1cc(C=O)ccc1C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
FDPS P14324 1/20 0.44
HPGD P15428 4/20 0.42
TRIM24 O15164 1/20 0.42
ALDH5A1 P51649 1/20 0.42
ABAT P80404 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
TSHR P16473 3/20 0.42
PDE4B Q07343 2/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
FLT3 P36888 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3464451 0.86 FDPS (0.54) ALDH1A1FDPSHPGDTRIM24ALDH5A1
SCHEMBL11721524 0.83 ALDH1A1 (0.68) ALDH1A1FDPSHPGDTRIM24ALDH5A1
SCHEMBL1520406 0.83 ALDH1A1 (0.47) ALDH1A1HPGDHTTSMN1; SMN2GAA
SCHEMBL10158234 0.81 ERN1 (0.40) ALDH1A1HPGDTSHRHTTSMN1; SMN2
SCHEMBL3954852 0.81 GAA (0.41) ALDH1A1HPGDTRIM24TRIM33TSHR
SCHEMBL23748178 0.81 MAPT (0.45) ALDH1A1HPGDTSHRHTTSMN1; SMN2
SCHEMBL2523798 0.81 GAA (0.55) ALDH1A1HPGDTDP1TSHRHTT
SCHEMBL4619965 0.81 HPGD (0.54) ALDH1A1HPGDTDP1TSHRHTT
SCHEMBL3694739 0.81 ERN1 (0.41) ALDH1A1HPGDTSHRHTTSMN1; SMN2
SCHEMBL28607462 0.81 ALDH1A1 (0.43) ALDH1A1HPGDTDP1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116392607-B Nano covalent organic framework for delivering NO and doping copper peroxide as well as preparation method and application thereof 山东师范大学 2025-07-11 CN disclosed
CN-116392607-A Nano covalent organic framework for delivering NO and doping copper peroxide as well as preparation method and application thereof 山东师范大学 2023-07-07 CN disclosed
EP-2863925-B1 SIALIC ACID DERIVATIVES BROSSMER REINHARD (DE) 2016-09-14 EP disclosed
EP-2044054-B1 PYRIMIDINE AND QUINAZOLINE DERIVATIVES AS MODULATORS OF SOMATOSTATINE RECEPTOR ACTIVITY HOFFMANN LA ROCHE (CH) 2011-06-08 EP disclosed