Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.37 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.37 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL17495601 | 0.82 | NAPRT (0.54) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| Benzophenone SCHEMBL27762502 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TDP1RAB9AMAPTLMNA | |
| Chalcone SCHEMBL28113459 | 0.81 | CYP1B1 (0.65) | ALDH1A1TDP1RAB9AMAPTLMNA | |
| Chalcone SCHEMBL27969784 | 0.81 | CYP1B1 (0.65) | ALDH1A1TDP1RAB9AMAPTLMNA | |
| Chalcone SCHEMBL28299193 | 0.80 | CYP1B1 (0.63) | ALDH1A1TDP1RAB9AMAPTLMNA | |
| Benzamide SCHEMBL19667939 | 0.79 | POLB (0.57) | ALDH1A1TDP1RAB9AMAPTRECQL | |
| Acetophenone SCHEMBL16114519 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1RAB9AMAPTLMNAMAOB | |
| SCHEMBL27970673 | 0.78 | KMT2A (0.33) | ALDH1A1LMNAMEN1KMT2AF2 | |
| SCHEMBL28061261 | 0.78 | KMT2A (0.33) | ALDH1A1LMNAMEN1KMT2AF2 | |
| Phenylglyoxal SCHEMBL57493 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPK1TDP1AKT1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340277-A1 | ANTIBODY COMPOUNDS WITH REACTIVE ARGININE AND RELATED ANTIBODY DRUG CONJUGATES | THE SCRIPPS RESEARCH INSTITUTE | 2021-11-04 | — | — | US | disclosed |
| CN-113329769-A | Antibody compounds with reactive arginine and related antibody drug conjugates | 斯克里普斯研究学院 | 2021-08-31 | — | — | CN | disclosed |
| EP-3863672-A1 | ANTIBODY COMPOUNDS WITH REACTIVE ARGININE AND RELATED ANTIBODY DRUG CONJUGATES | The Scripps Research Institute (US) | 2021-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340277-A1 | ANTIBODY COMPOUNDS WITH REACTIVE ARGININE AND RELATED ANTIBODY DRUG CONJUGATES | RAB29, RAB39A, RAB5C | ALDH1A1 1868/4885MAPK1 3854/4885TDP1 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.