Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25170812 | 0.88 | PARP1 (0.47) | POLBCYP3A4PARP1MAPTTSHR | |
| Benzophenone SCHEMBL27762502 | 0.85 | ALDH1A1 (0.54) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| Benzoic Acid SCHEMBL17495601 | 0.85 | NAPRT (0.54) | TSHRKMT2AALDH1A1MEN1 | |
| Acetophenone SCHEMBL16114519 | 0.82 | SMN1; SMN2 (0.46) | MAPTTSHRL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL28061261 | 0.81 | KMT2A (0.33) | CYP3A4TSHRCYP2C19KMT2AALDH1A1 | |
| SCHEMBL27970673 | 0.81 | KMT2A (0.33) | CYP3A4TSHRCYP2C19KMT2AALDH1A1 | |
| Carbamic Acid SCHEMBL1682079 | 0.80 | — | — | |
| SCHEMBL28016232 | 0.79 | MEN1 (0.32) | TSHRKMT2AALDH1A1MEN1 | |
| Benzoic Acid SCHEMBL380582 | 0.79 | NAPRT (0.47) | CYP3A4TSHRCYP2C19TDP1L3MBTL1 | |
| Phenylglyoxal SCHEMBL23748334 | 0.79 | ALDH1A1 (0.60) | CYP3A4MAPTTSHRRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104109166-A | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | SHANGHAI PHARMACEUTICALS HOLDING CO LTD | 2014-10-22 | — | — | CN | claimed |
| CN-1526704-A | Substituted triazolformamide compound | 拜尔农作物科学股份公司 | 2004-09-08 | — | — | CN | claimed |
| CN-1200652-A | Herbicidal mixtures with synergistic activity | BASF AG (DE) | 1998-12-02 | — | — | CN | claimed |
| EP-3817811-B1 | TRIAZOLE BENZAMIDE DERIVATIVES AS GPR142 AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2024-04-03 | — | — | EP | disclosed |
| CN-112368049-B | Triazole benzamide derivatives as GPR142 agonists | 勃林格殷格翰国际有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112368049-B | Triazole benzamide derivatives as GPR142 agonists | 勃林格殷格翰国际有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114249692-B | 2-imidazole benzamide active compound for preventing and treating wheat take-all and wheat stem basal rot | 河南农业大学 | 2024-01-30 | — | — | CN | disclosed |
| US-11179371-B2 | Triazole benzamide derivatives as GPR142 agonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-11-23 | — | — | US | disclosed |
| US-11179371-B2 | Triazole benzamide derivatives as GPR142 agonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-11-23 | — | — | US | disclosed |
| US-20210230126-A1 | ASYMMETRIC TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | NYSNOBIO IRELAND DAC (IE) | 2021-07-29 | — | — | US | disclosed |
| US-20210230126-A1 | ASYMMETRIC TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | NYSNOBIO IRELAND DAC (IE) | 2021-07-29 | — | — | US | disclosed |
| CN-1246035-A | Sulphonyl urea and adjuvant based solid mixture | BASF AG (DE) | 2000-03-01 | — | — | CN | disclosed |
| CN-1245487-A | Herbicidal 3-aminocarbonyl-or 3-aminothiocarbonyl-substituted 2-benzoylcyclohexane-1, 3-diones | BASF AG (DE) | 2000-02-23 | — | — | CN | disclosed |
| CN-1245488-A | Substituted 2-benzoyl-cyclohexan-1,3-diones with herbicidal effect | BASF AG (DE) | 2000-02-23 | — | — | CN | disclosed |
| CN-1230951-A | Herbicidal heteroaroyl cyclohexanedione derivatives | BASF AG (DE) | 1999-10-06 | — | — | CN | disclosed |
| CN-1211979-A | 2-hetaroylcyclohexane-1,3-diones | BASF AG (DE) | 1999-03-24 | — | — | CN | disclosed |
| CN-1211249-A | Pyrazol-4-yl heteroaroyl derivatives as herbicides | BASF AG (DE) | 1999-03-17 | — | — | CN | disclosed |
| CN-1200652-A | Herbicidal mixtures with synergistic activity | BASF AG (DE) | 1998-12-02 | — | — | CN | disclosed |
| CN-1194644-A | Pyrazol-4-yl-benzoyl derivatives and their use as herbicides | BASF AG (DE) | 1998-09-30 | — | — | CN | disclosed |
| CN-1194641-A | 2-cyclohexane-1,3-dione benzoyl derivatives | BASF AG (DE) | 1998-09-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11179371-B2 | Triazole benzamide derivatives as GPR142 agonists | GPR119, GPR142, GPR65 | POLB 4750/4885CYP3A4 1194/4885PARP1 3101/4885 |
| US-20210230126-A1 | ASYMMETRIC TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | ATG7, PINK1, ADRM1 | POLB 1629/4885CYP3A4 1419/4885PARP1 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.