Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24120301 | 0.92 | ALDH1A1 (0.39) | ACHEPOLBALDH1A1CYP1A2LMNA | |
| SCHEMBL21344670 | 0.90 | CHRM2 (0.42) | GRM5ACHEPOLBHTTCRBN | |
| SCHEMBL24120434 | 0.88 | GPR183 (0.43) | ALDH1A1 | |
| SCHEMBL24120470 | 0.87 | L3MBTL1 (0.42) | GRM5MGLLALDH1A1LMNA | |
| SCHEMBL24120410 | 0.85 | L3MBTL1 (0.40) | EPHX2ALDH1A1EPHX1 | |
| SCHEMBL24120331 | 0.85 | HTT (0.41) | HTTMGLLALDH1A1LMNAMAPK1 | |
| SCHEMBL23748396 | 0.84 | — | — | |
| SCHEMBL24120380 | 0.84 | TLR9 (0.33) | MGLLALDH1A1 | |
| SCHEMBL21344240 | 0.83 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CHRM2CHRM3MAPK1 | |
| SCHEMBL24120362 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398101-B2 | Herbicidal 2-azaspiro[3-5]nonane compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-08-26 | — | — | US | disclosed |
| CN-112823150-B | Herbicidal 2-azaspiro [3-5] nonane compounds | 先正达农作物保护股份公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-3864006-B1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-11-16 | — | — | EP | disclosed |
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
| EP-3864006-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | DDT, AZI2, CBR3 | GRM5 275/4885ACHE 46/4885POLB 3716/4885 |
| US-12398101-B2 | Herbicidal 2-azaspiro[3-5]nonane compounds | DDT, AZI2, CBR3 | GRM5 275/4885ACHE 46/4885POLB 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.