Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24120301 | 0.86 | ALDH1A1 (0.39) | LMNAALDH1A1HPGDDRD3KMT2A | |
| SCHEMBL23748397 | 0.85 | GRM5 (0.35) | HTTLMNAALDH1A1MAPK1MGLL | |
| SCHEMBL24120434 | 0.83 | GPR183 (0.43) | TSHRUSP2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL24120470 | 0.83 | L3MBTL1 (0.42) | LMNAALDH1A1HPGDDRD3CA12 | |
| SCHEMBL24120297 | 0.82 | PDE4B (0.38) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL24120373 | 0.81 | NNMT (0.34) | — | |
| SCHEMBL24120288 | 0.81 | — | — | |
| SCHEMBL24120410 | 0.81 | L3MBTL1 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL24426554 | 0.80 | ALDH1A1 (0.43) | HTTMAPTALDH1A1HPGDCYP2C9 | |
| SCHEMBL23748396 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | DDT, AZI2, CBR3 | HTT 2090/4885HCRTR1 160/4885HCRTR2 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.