Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 6/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22941926 | 0.94 | ROCK2 (0.37) | ROCK2EHMT2ACACBRORCKDM4E | |
| SCHEMBL21285092 | 0.89 | GPR119 (0.42) | ACACBKDM4EMAPTTHRBLMNA | |
| SCHEMBL23748398 | 0.84 | GPR183 (0.38) | EHMT2ACACBKDM4EMAPTTHRB | |
| SCHEMBL23748413 | 0.83 | HDAC2 (0.48) | EHMT2RORCKRAS | |
| SCHEMBL22908416 | 0.81 | DPP4 (0.40) | ACACBGPR183DPP4NOTCH1 | |
| SCHEMBL22941742 | 0.80 | GPR183 (0.36) | EHMT2ACACBKDM4EMAPTTHRB | |
| SCHEMBL21344641 | 0.79 | ACACB (0.42) | ACACBKDM4EMAPTTHRB | |
| SCHEMBL22954915 | 0.78 | GPR119 (0.50) | KDM4EMAPTTHRB | |
| SCHEMBL22941597 | 0.76 | KDM1A (0.36) | — | |
| SCHEMBL21273942 | 0.74 | GPR183 (0.41) | ACACBKDM4EMAPTTHRBGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398101-B2 | Herbicidal 2-azaspiro[3-5]nonane compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-08-26 | — | — | US | disclosed |
| CN-112823150-B | Herbicidal 2-azaspiro [3-5] nonane compounds | 先正达农作物保护股份公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-3864006-B1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-11-16 | — | — | EP | disclosed |
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
| EP-3864006-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-08-18 | — | — | EP | disclosed |
| CN-112823150-A | Herbicidal 2-azaspiro [3-5] nonane compounds | 先正达农作物保护股份公司 | 2021-05-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | DDT, AZI2, CBR3 | ROCK2 1905/4885EHMT2 136/4885ACACB 2004/4885 |
| US-12398101-B2 | Herbicidal 2-azaspiro[3-5]nonane compounds | DDT, AZI2, CBR3 | ROCK2 1905/4885EHMT2 136/4885ACACB 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.