Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361282 | 0.90 | HDAC2 (0.53) | HDAC2HDAC1MMP13PTPN2PTPN1 | |
| SCHEMBL24120384 | 0.86 | HDAC2 (0.37) | HDAC2HDAC1HDAC3 | |
| SCHEMBL23748414 | 0.85 | HDAC2 (0.48) | HDAC2HDAC1HDAC3 | |
| SCHEMBL24120140 | 0.84 | HDAC2 (0.41) | HDAC2HDAC1RORCHDAC3 | |
| SCHEMBL23748412 | 0.83 | ROCK2 (0.38) | RORCKRASEHMT2 | |
| SCHEMBL24120397 | 0.82 | HDAC2 (0.37) | HDAC2HDAC1HDAC3 | |
| SCHEMBL24120304 | 0.82 | HDAC2 (0.40) | HDAC2HDAC1RORCHDAC3 | |
| SCHEMBL24120391 | 0.82 | RORC (0.34) | HDAC2HDAC1RORCJAK2JAK1 | |
| SCHEMBL24120354 | 0.82 | HSD17B10 (0.39) | HDAC2HDAC1RORCMEN1KMT2A | |
| SCHEMBL24120371 | 0.82 | HDAC2 (0.37) | HDAC2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398101-B2 | Herbicidal 2-azaspiro[3-5]nonane compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-08-26 | — | — | US | disclosed |
| CN-112823150-B | Herbicidal 2-azaspiro [3-5] nonane compounds | 先正达农作物保护股份公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-3864006-B1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-11-16 | — | — | EP | disclosed |
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
| EP-3864006-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | DDT, AZI2, CBR3 | HDAC2 490/4885HDAC1 246/4885MMP13 3657/4885 |
| US-12398101-B2 | Herbicidal 2-azaspiro[3-5]nonane compounds | DDT, AZI2, CBR3 | HDAC2 490/4885HDAC1 246/4885MMP13 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.