Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.52 |
| ▸ | CCND1 | P24385 | 1/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896267 | 0.89 | MAPT (0.47) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL10960804 | 0.87 | MEN1 (0.49) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL15013285 | 0.86 | MAPT (0.55) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL2655836 | 0.84 | RAB9A (0.67) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL2655835 | 0.84 | RAB9A (0.67) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9976442 | 0.83 | HPD (0.47) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL10535540 | 0.82 | CCNB2 (0.46) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL10535536 | 0.82 | CCNB2 (0.46) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL860576 | 0.81 | MEN1 (0.47) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8026962 | 0.81 | MEN1 (0.47) | CCNB2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864013-A1 | THYROID HORMONE RECEPTOR AGONISTS | InventisBio Co., Ltd. (CN) | 2021-08-18 | — | — | EP | disclosed |