Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.40 |
| ▸ | F7 | P08709 | 3/20 | 0.40 |
| ▸ | F3 | P13726 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610783 | 0.90 | F7 (0.52) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL23748651 | 0.90 | F7 (0.52) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL2817104 | 0.86 | FOLH1 (0.54) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL2817110 | 0.86 | FOLH1 (0.54) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL16240898 | 0.85 | HMGB1 (0.62) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL235534 | 0.85 | HMGB1 (0.62) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL31354821 | 0.85 | HMGB1 (0.62) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL8395993 | 0.85 | HMGB1 (0.62) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL7950463 | 0.84 | G6PD (0.47) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL18604012 | 0.84 | G6PD (0.47) | HMGB1BIDBCL2L1MCL1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-12-09 | — | — | US | disclosed |
| EP-3864001-A1 | ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | GLS2, FFAR3, SLC10A1 | HMGB1 2051/4885MRGPRX4 419/4885BID 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.