Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.43 |
| ▸ | F7 | P08709 | 3/20 | 0.43 |
| ▸ | F3 | P13726 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16240898 | 1.00 | HMGB1 (0.62) | HMGB1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL235534 | 1.00 | HMGB1 (0.62) | HMGB1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL31354821 | 1.00 | HMGB1 (0.62) | HMGB1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL5056707 | 0.91 | ALDH1A1 (0.52) | HMGB1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL2817104 | 0.86 | FOLH1 (0.54) | HMGB1KDM4EHSD17B10ALDH1A1BID | |
| SCHEMBL2817110 | 0.86 | FOLH1 (0.54) | HMGB1KDM4EHSD17B10ALDH1A1BID | |
| SCHEMBL23748665 | 0.85 | HMGB1 (0.43) | HMGB1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL30853556 | 0.85 | HMGB1 (0.46) | HMGB1KDM4EHSD17B10ALDH1A1BID | |
| SCHEMBL7950463 | 0.84 | G6PD (0.47) | HMGB1KDM4EHSD17B10ALDH1A1BID | |
| SCHEMBL18604012 | 0.84 | G6PD (0.47) | HMGB1KDM4EHSD17B10ALDH1A1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761808-B1 | Use of substituted lactones as perfuming agent | HAARMANN & REIMER GMBH (DE) | 1999-05-19 | — | — | EP | disclosed |
| EP-0761808-A2 | Use of substituted lactones as perfuming agent | HAARMANN & REIMER GMBH (DE) | 1997-03-12 | — | — | EP | disclosed |
| EP-0094722-B1 | 10-ISOPROPYL-2,7-DIMETHYL-1-OXASPIRO(4.5)DECA-3,6-DIENE, ITS USE IN PERFUMES AND AROMAS | NAARDEN INTERNATIONAL N.V. (NL) | 1986-02-26 | — | — | EP | disclosed |
| EP-0094722-A1 | 10-Isopropyl-2,7-dimethyl-1-oxaspiro(4.5)deca-3,6-diene, its use in perfumes and aromas | NAARDEN INTERNATIONAL N.V. (NL) | 1983-11-23 | — | — | EP | disclosed |