SCHEMBL2817110

SCHEMBL2817110

CCC=CCCc1ccccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.54
CLCN2 P51788 1/20 0.43
HMGB1 P09429 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 2/20 0.42
SLC16A3 O15427 3/20 0.42
GPR52 Q9Y2T5 2/20 0.41
MAPT P10636 2/20 0.41
FFAR1 O14842 1/20 0.41
CYP19A1 P11511 1/20 0.41
RXRA P19793 1/20 0.41
PPARG P37231 1/20 0.41
OXER1 Q8TDS5 1/20 0.41
EPHX2 P34913 2/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
BID P55957 2/20 0.40
BCL2L1 Q07817 2/20 0.40
MCL1 Q07820 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2817104 1.00 FOLH1 (0.54) FOLH1CLCN2HMGB1TSHRALDH1A1
SCHEMBL8395993 0.86 HMGB1 (0.62) CLCN2HMGB1ALDH1A1ALOX15MAPT
SCHEMBL16240898 0.86 HMGB1 (0.62) CLCN2HMGB1ALDH1A1ALOX15MAPT
SCHEMBL235534 0.86 HMGB1 (0.62) CLCN2HMGB1ALDH1A1ALOX15MAPT
SCHEMBL31354821 0.86 HMGB1 (0.62) CLCN2HMGB1ALDH1A1ALOX15MAPT
SCHEMBL23748665 0.86 HMGB1 (0.43) FOLH1CLCN2HMGB1TSHRALDH1A1
SCHEMBL30853560 0.85 LMNA (0.48) FOLH1TSHRALDH1A1SLC16A3GPR52
SCHEMBL1883430 0.85 LMNA (0.48) FOLH1TSHRALDH1A1SLC16A3GPR52
SCHEMBL18604012 0.84 G6PD (0.47) FOLH1CLCN2HMGB1ALDH1A1ALOX15
SCHEMBL7950463 0.84 G6PD (0.47) FOLH1CLCN2HMGB1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111885916-B Solid polymeric material impregnated with volatile organic substances and with specific esters and use thereof 加法尔企业R&D公司 2022-08-05 CN disclosed
US-11278857-B2 Polymeric capsules THE PROCTER & GAMBLE COMPANY (US) 2022-03-22 US disclosed
CN-111885916-A Solid polymeric material impregnated with volatile organic substances and with specific esters and use thereof 加法尔企业R&D公司 2020-11-03 CN disclosed
CN-111378531-A Method for extracting jasmine flower fragrance substance and flower fragrance solution obtained by same 兰星平 2020-07-07 CN disclosed
US-9200269-B2 β-glucuronidase inhibitor KAO CORPORATION (JP) 2015-12-01 US disclosed
US-9120741-B2 Transition metal catalysts for hydrogenation and hydrosilylation GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2015-09-01 US disclosed
US-20140179946-A1 TRANSITION METAL CATALYSTS FOR HYDROGENATION AND HYDROSILYLATION GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2014-06-26 US disclosed
CN-102159309-B A fragrance-delivery composition comprising boron and persulfate ion-crosslinked polyvinyl alcohol microcapsules and method of use thereof APPLETON PAPER INC 2014-06-18 CN disclosed
CN-102159309-A A fragrance-delivery composition comprising boron and persulfate ion-crosslinked polyvinyl alcohol microcapsules and method of use thereof APPLETON PAPER INC 2011-08-17 CN disclosed
US-20100247475-A1 BETA-GLUCURONIDASE INHIBITOR KAO CORPORATION (JP) 2010-09-30 US disclosed
EP-2192178-A1 B-GLUCURONIDASE INHIBITOR Kao Corporation (JP) 2010-06-02 EP disclosed
EP-1010686-A1 New Tetrahydronaphthalenes Givaudan Roure (International) S.A. (CH) 2000-06-21 EP disclosed
EP-1010685-A1 New tetrahydronaphthalenes Givaudan Roure (International) S.A. (CH) 2000-06-21 EP disclosed
US-5800897-A Air freshener composition containing a fiber pad EASTMAN CHEMICAL COMPANY (US) 1998-09-01 US disclosed
WO-1997026926-A1 AIR FRESHENER COMPOSITION CONTAINING A FIBER PAD EASTMAN CHEMICAL COMPANY (US) 1997-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140179946-A1 TRANSITION METAL CATALYSTS FOR HYDROGENATION AND HYDROSILYLATION HVCN1, SLC9A1, SLC9A3 FOLH1 4000/4885CLCN2 1141/4885HMGB1 798/4885
US-20100247475-A1 BETA-GLUCURONIDASE INHIBITOR GUSB, GAA, GANAB FOLH1 285/4885CLCN2 1346/4885HMGB1 4563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.