Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355128 | 1.00 | LMNA (0.44) | LMNAF10PRSS1MMP3GRM8 | |
| SCHEMBL2350428 | 0.97 | LMNA (0.43) | LMNAF10PRSS1MMP3GRM8 | |
| SCHEMBL2353245 | 0.94 | CYP2D6 (0.41) | LMNAF10PRSS1MMP3GRM8 | |
| SCHEMBL2355830 | 0.87 | NPSR1 (0.38) | LMNAMMP3CYP2D6ITGB3ITGA2B | |
| SCHEMBL2348810 | 0.87 | KDM4E (0.41) | GRM8GRM4S1PR1S1PR4S1PR3 | |
| SCHEMBL2353764 | 0.86 | MMP3 (0.37) | LMNAF10MMP3GRM8GRM4 | |
| SCHEMBL2356284 | 0.83 | GRB2 (0.37) | LMNAF10GAAITGB3ITGA2B | |
| SCHEMBL6103215 | 0.83 | KDM4E (0.36) | LMNAF10MMP3GRM8GRM4 | |
| SCHEMBL2351043 | 0.83 | ALDH1A1 (0.39) | LMNAF10POLBKMT2AMEN1 | |
| SCHEMBL2352129 | 0.82 | CPN1 (0.39) | F10ITGB3ITGA2BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |