SCHEMBL23752198

SCHEMBL23752198

O=C(O)c1ccc2c(c1)C(=O)N([C@H](Cc1cccc3ccccc13)C(=O)O)C2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.68
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
CYP2D6 P10635 1/20 0.59
TDP1 Q9NUW8 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21068022 1.00 L3MBTL1 (0.68) L3MBTL1MEN1KMT2ACYP2D6TDP1
SCHEMBL28930271 0.89 KMT2A (0.63) L3MBTL1MEN1KMT2ACYP2D6
SCHEMBL28930272 0.89 KMT2A (0.63) L3MBTL1MEN1KMT2ACYP2D6
SCHEMBL29459355 0.89 KMT2A (0.63) L3MBTL1MEN1KMT2ACYP2D6
SCHEMBL21067836 0.85 L3MBTL1 (0.52) L3MBTL1MEN1KMT2ACYP2D6TDP1
SCHEMBL23752385 0.85 L3MBTL1 (0.52) L3MBTL1MEN1KMT2ACYP2D6TDP1
SCHEMBL28678717 0.78 KMT2A (0.49) L3MBTL1MEN1KMT2ACYP2D6TDP1
SCHEMBL28678716 0.78 KMT2A (0.49) L3MBTL1MEN1KMT2ACYP2D6TDP1
SCHEMBL29459444 0.78 KMT2A (0.49) L3MBTL1MEN1KMT2ACYP2D6TDP1
SCHEMBL8085365 0.74 ALDH1A1 (0.68) L3MBTL1MEN1KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed