Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28930272 | 1.00 | KMT2A (0.63) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL28930271 | 1.00 | KMT2A (0.63) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL23752198 | 0.89 | L3MBTL1 (0.68) | KMT2ACYP2D6L3MBTL1MEN1 | |
| SCHEMBL21068022 | 0.89 | L3MBTL1 (0.68) | KMT2ACYP2D6L3MBTL1MEN1 | |
| SCHEMBL28678717 | 0.88 | KMT2A (0.49) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL29459444 | 0.88 | KMT2A (0.49) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL28678716 | 0.88 | KMT2A (0.49) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL8085365 | 0.84 | ALDH1A1 (0.68) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL8085370 | 0.84 | ALDH1A1 (0.68) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL18258645 | 0.78 | NPSR1 (0.59) | KMT2ACYP2C19HPGDHSD17B10CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924349-B1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | THE ROSKAMP INST (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20220081415-A1 | Amino Acid Derivatives for the Treatment of Inflammatory Diseases | THE ROSKAMP INST (US) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081415-A1 | Amino Acid Derivatives for the Treatment of Inflammatory Diseases | NFKBIA, NFRKB, IKBKG | KMT2A 2451/4885DNMT1 2271/4885CYP2C19 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.