Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754127 | 0.69 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL23363064 | 0.62 | PDE2A (0.34) | — | |
| SCHEMBL23363065 | 0.62 | PDE2A (0.34) | — | |
| SCHEMBL29757466 | 0.62 | PDE2A (0.34) | — | |
| SCHEMBL10172743 | 0.62 | SMN1; SMN2 (0.48) | ADCY10 | |
| SCHEMBL7698240 | 0.59 | USP2 (0.45) | — | |
| SCHEMBL27676185 | 0.59 | GRIA2 (0.44) | ADCY10 | |
| SCHEMBL19556155 | 0.59 | L3MBTL1 (0.42) | — | |
| SCHEMBL3234799 | 0.59 | GABRP (0.60) | — | |
| SCHEMBL31143168 | 0.59 | GABRP (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103562-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |