Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23753737 | 0.82 | JAK1 (0.53) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL23754207 | 0.81 | JAK1 (0.51) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL23754392 | 0.81 | JAK2 (0.51) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL23764040 | 0.77 | JAK1 (0.48) | SMN1; SMN2TP53MAPTKMT2ANPC1 | |
| SCHEMBL23764043 | 0.76 | JAK1 (0.42) | SMN1; SMN2TP53MAPTLMNAJAK1 | |
| SCHEMBL23754203 | 0.76 | JAK2 (0.47) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL23754210 | 0.75 | MAPT (0.46) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL18341116 | 0.74 | AHR (0.49) | SMN1; SMN2MEN1KMT2AJAK1KDM4E | |
| SCHEMBL23764045 | 0.73 | IL2 (0.52) | SMN1; SMN2TP53JAK1 | |
| SCHEMBL28485655 | 0.73 | AHR (0.47) | KDM4EALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161084-A1 | N-(4-FLUOROPHENYL)-5-PHENYL-[1,2,4] TRIAZOLO [1,5-A] PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND THEIR SYNTHESIS THEREOF | NINGEGOWDA RAGHU (IN) | 2021-08-19 | — | — | WO | disclosed |
| WO-2021161084-A1 | N-(4-FLUOROPHENYL)-5-PHENYL-[1,2,4] TRIAZOLO [1,5-A] PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND THEIR SYNTHESIS THEREOF | NINGEGOWDA RAGHU (IN) | 2021-08-19 | — | — | WO | disclosed |