Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754207 | 0.85 | JAK1 (0.51) | JAK1SMN1; SMN2TP53MAPTIDO1 | |
| SCHEMBL23754210 | 0.85 | MAPT (0.46) | JAK1SMN1; SMN2TP53MAPTKCNK3 | |
| SCHEMBL23754203 | 0.84 | JAK2 (0.47) | JAK1SMN1; SMN2TP53MAPTABL1 | |
| SCHEMBL23753737 | 0.80 | JAK1 (0.53) | JAK1SMN1; SMN2TP53MAPTLMNA | |
| SCHEMBL23764045 | 0.77 | IL2 (0.52) | JAK1SMN1; SMN2TP53IDO1JAK2 | |
| SCHEMBL23754392 | 0.76 | JAK2 (0.51) | JAK1SMN1; SMN2TP53MAPTIDO1 | |
| SCHEMBL23754239 | 0.76 | SMN1; SMN2 (0.46) | JAK1SMN1; SMN2TP53MAPTLMNA | |
| SCHEMBL23764040 | 0.73 | JAK1 (0.48) | JAK1SMN1; SMN2TP53MAPTJAK2 | |
| SCHEMBL14896757 | 0.66 | NAMPT (0.45) | NAMPTSCN10A | |
| SCHEMBL19659253 | 0.64 | EGLN2 (0.50) | JAK1JAK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161084-A1 | N-(4-FLUOROPHENYL)-5-PHENYL-[1,2,4] TRIAZOLO [1,5-A] PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND THEIR SYNTHESIS THEREOF | NINGEGOWDA RAGHU (IN) | 2021-08-19 | — | — | WO | disclosed |