SCHEMBL237552

SCHEMBL237552

CC(C)(c1ccccc1)c1ccc(OC(=O)Oc2ccc(C(C)(C)c3ccccc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
MAPT P10636 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 7/20 0.53
ESR1 P03372 1/20 0.53
CYP3A4 P08684 1/20 0.53
ESR2 Q92731 1/20 0.53
KDM4E B2RXH2 10/20 0.53
POLB P06746 2/20 0.53
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
HTT P42858 2/20 0.51
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
LMNA P02545 2/20 0.48
ELANE P08246 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247689 0.98 TDP1 (0.53) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL13924997 0.96 L3MBTL1 (0.54) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL235938 0.95 TDP1 (0.50) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL12313792 0.95 MAPT (0.63) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL3424446 0.93 KDM4E (0.50) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL11949463 0.93 ALDH1A1 (0.67) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL12220669 0.93 ALDH1A1 (0.49) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL10027744 0.93 TDP1 (0.49) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL16488968 0.93 TDP1 (0.49) TDP1MAPTL3MBTL1ALDH1A1ESR1
SCHEMBL11617807 0.93 ALDH1A1 (0.49) TDP1MAPTL3MBTL1ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599706-B Process for preparing polyester carbonates 科思创德国股份有限公司 2025-02-18 CN claimed
EP-4055080-A1 PROCESS FOR PREPARING POLYESTER CARBONATES Covestro Intellectual Property GmbH & Co. KG (DE) 2022-09-14 EP claimed
CN-114599706-A Method for producing polyester carbonates 科思创知识产权两合公司 2022-06-07 CN claimed
EP-2457891-B1 Method for manufacturing diaryl carbonates from dialkyl carbonates BAYER IP GMBH (DE) 2015-04-01 EP claimed
EP-2655383-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX Polymers, Inc. (US) 2013-10-30 EP claimed
EP-2655384-A2 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX Polymers, Inc. (US) 2013-10-30 EP claimed
US-8563638-B2 Oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-10-22 US claimed
EP-2650278-A1 Method for manufacturing diaryl carbonates from dialkyl carbonates Bayer MaterialScience AG (DE) 2013-10-16 EP claimed
US-8530044-B2 Hyperbranched oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-09-10 US claimed
US-8304509-B2 Process for preparing diaryl carbonates from dialkyl carbonates BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-11-06 US claimed
WO-2012088406-A2 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-06-28 WO claimed
WO-2012088435-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-06-28 WO claimed
EP-2457891-A1 Method for manufacturing diaryl carbonates from dialkyl carbonates Bayer MaterialScience AG (DE) 2012-05-30 EP claimed
US-20120101247-A1 PROCESS FOR PREPARING DIARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2012-04-26 US claimed
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP claimed
EP-1436343-B8 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC (US) 2007-04-11 EP claimed
EP-1436343-B1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC COMPANY A CORP OF (US) 2006-11-02 EP claimed
EP-1436343-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME General Electric Company A Corporation of the State of New York (US) 2004-07-14 EP claimed
WO-2003031497-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GENERAL ELECTRIC COMPANY (US) 2003-04-17 WO claimed
US-6500914-B1 MELT TRANSESTERIFICATION OF FREE HYDROXYL TERMINAL GROUPS WITH A DIARYL CARBONATE GENERAL ELECTRIC COMPANY 2002-12-31 US claimed