SCHEMBL247689

SCHEMBL247689

CC(C)(c1ccccc1)c1ccc(OC(=O)Oc2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPT P10636 1/20 0.53
ALDH1A1 P00352 7/20 0.52
ESR1 P03372 1/20 0.52
CYP3A4 P08684 1/20 0.52
ESR2 Q92731 1/20 0.52
KDM4E B2RXH2 10/20 0.51
POLB P06746 2/20 0.51
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
HTT P42858 2/20 0.50
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
LMNA P02545 2/20 0.47
ATM Q13315 1/20 0.45
ELANE P08246 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237552 0.98 TDP1 (0.54) TDP1L3MBTL1MAPTALDH1A1ESR1
SCHEMBL13924997 0.98 L3MBTL1 (0.54) TDP1L3MBTL1MAPTALDH1A1ESR1
SCHEMBL9349408 0.93 ALDH1A1 (0.65) TDP1L3MBTL1MAPTALDH1A1ESR1
SCHEMBL23861988 0.93 MAPT (0.50) TDP1L3MBTL1MAPTALDH1A1ESR1
SCHEMBL12313792 0.93 MAPT (0.63) TDP1L3MBTL1MAPTALDH1A1ESR1
SCHEMBL235938 0.93 TDP1 (0.50) TDP1L3MBTL1MAPTALDH1A1ESR1
SCHEMBL15831653 0.91 ESR1 (0.61) TDP1L3MBTL1MAPTALDH1A1ESR1
SCHEMBL13476677 0.91 ALDH1A1 (0.49) TDP1L3MBTL1MAPTALDH1A1KDM4E
SCHEMBL3424446 0.91 KDM4E (0.50) TDP1L3MBTL1MAPTALDH1A1ESR1
SCHEMBL10027744 0.91 TDP1 (0.49) TDP1L3MBTL1MAPTALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2457891-B1 Method for manufacturing diaryl carbonates from dialkyl carbonates BAYER IP GMBH (DE) 2015-04-01 EP claimed
EP-2650278-A1 Method for manufacturing diaryl carbonates from dialkyl carbonates Bayer MaterialScience AG (DE) 2013-10-16 EP claimed
US-8304509-B2 Process for preparing diaryl carbonates from dialkyl carbonates BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-11-06 US claimed
EP-2457891-A1 Method for manufacturing diaryl carbonates from dialkyl carbonates Bayer MaterialScience AG (DE) 2012-05-30 EP claimed
US-20120101247-A1 PROCESS FOR PREPARING DIARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2012-04-26 US claimed
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP claimed
US-5151491-A Nitrogen compound, a boric acid compound and a dihydroxy compound terminated with a monoalcohol GE PLASTICS JAPAN, LTD. (JP) 1992-09-29 US claimed
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures COVESTRO DEUTSCHLAND AG (DE) 2026-04-14 US disclosed
EP-3055342-B1 PROCESS FOR PREPARING POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES USING A SALT OF A WEAK ACID COVESTRO DEUTSCHLAND AG (DE) 2026-03-04 EP disclosed
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio COVESTRO DEUTSCHLAND AG (DE) 2026-01-27 US disclosed
US-12516152-B2 Polyester carbonates having a defined proportion of ester groups COVESTRO DEUTSCHLAND AG (DE) 2026-01-06 US disclosed
US-20250381764-A1 Multi-Layer Film With Improved Modulus Properties COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-12-18 US disclosed
US-12473397-B2 Polyester carbonates from aliphatic diacids and aliphatic diols, and process for the production thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2025-11-18 US disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276129-A Aromatic polycarbonates with excellent color tone, heat resistance and water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-01-04 US disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
US-5151491-A Nitrogen compound, a boric acid compound and a dihydroxy compound terminated with a monoalcohol GE PLASTICS JAPAN, LTD. (JP) 1992-09-29 US disclosed
EP-0360578-A2 Process for the production of polycarbonates GE PLASTICS JAPAN LTD. (JP) 1990-03-28 EP disclosed
US-4096168-A PHENOL, CARBON MONOXIDE, GROUP 8B CATALYST, POLYCARBONATES FROM POLYPHENOLS GENERAL ELECTRIC COMPANY (US) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures ASH2L, SMC2, ELL TDP1 3125/4885L3MBTL1 24/4885MAPT 509/4885
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio HSD11B2, HSD11B1, HSD3B1 TDP1 2330/4885L3MBTL1 4164/4885MAPT 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.