Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23758265 | 0.95 | RAB9A (0.59) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL23758262 | 0.94 | GSK3B (0.56) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL23758264 | 0.94 | RAB9A (0.64) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL23758256 | 0.89 | ADORA3 (0.63) | RAB9ANPC1TP53SMN1; SMN2KMT2A | |
| SCHEMBL23758259 | 0.85 | ADORA3 (0.69) | RAB9ANPC1TP53SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL31679087 | 0.84 | ADORA3 (0.67) | RAB9ANPC1TP53SMN1; SMN2KMT2A | |
| SCHEMBL23758254 | 0.84 | ADORA3 (0.64) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL23758257 | 0.84 | KMT2A (0.57) | RAB9ANPC1TP53SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL31679105 | 0.83 | ADORA3 (0.63) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL23758260 | 0.82 | PTPN1 (0.58) | SMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11090289-B2 | Compositions and methods for blocking sodium channels | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11090289-B2 | Compositions and methods for blocking sodium channels | SCN3A, SCN1B, SCN2B | RAB9A 2068/4885NPC1 483/4885TP53 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.