Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22035870 | 0.90 | L3MBTL1 (0.44) | L3MBTL1KDM4EATMTSPOALDH1A1 | |
| SCHEMBL22036701 | 0.86 | KDM4E (0.55) | L3MBTL1KDM4EATMALDH1A1MEN1 | |
| SCHEMBL23760172 | 0.84 | L3MBTL1 (0.44) | L3MBTL1KDM4EATMTSPOALDH1A1 | |
| SCHEMBL23760169 | 0.84 | L3MBTL1 (0.47) | L3MBTL1KDM4EATMTSPOALDH1A1 | |
| SCHEMBL23760161 | 0.84 | L3MBTL1 (0.47) | L3MBTL1KDM4EATMTSPOALDH1A1 | |
| SCHEMBL22036321 | 0.83 | L3MBTL1 (0.46) | L3MBTL1KDM4EATMTSPOALDH1A1 | |
| SCHEMBL22035832 | 0.83 | KDM4E (0.49) | L3MBTL1KDM4EATMALDH1A1MEN1 | |
| SCHEMBL23760199 | 0.82 | L3MBTL1 (0.47) | L3MBTL1KDM4EATMALDH1A1MEN1 | |
| SCHEMBL23760213 | 0.82 | ABCG2 (0.37) | ATMTSPOALDH1A1MEN1KMT2A | |
| SCHEMBL21453818 | 0.82 | KDM4E (0.50) | L3MBTL1KDM4EATMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |