Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | BMX | P51813 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760181 | 0.85 | L3MBTL1 (0.36) | HSD17B10MAPTHPGDKMT2AMEN1 | |
| SCHEMBL23760141 | 0.83 | EGFR (0.43) | HSD17B10TSHRMAPTMAPK1NPSR1 | |
| SCHEMBL22036724 | 0.82 | MAPT (0.42) | HSD17B10TSHRMAPTMAPK1NPSR1 | |
| SCHEMBL23760117 | 0.79 | IL1R1 (0.43) | HSD17B10TSHRMAPTMAPK1HPGD | |
| SCHEMBL22036066 | 0.77 | MAPT (0.42) | HSD17B10TSHRMAPTMAPK1NPSR1 | |
| SCHEMBL23760174 | 0.77 | ALDH1A1 (0.37) | HSD17B10MAPTPDE10AKMT2AMEN1 | |
| SCHEMBL23760203 | 0.76 | L3MBTL1 (0.36) | HSD17B10MAPTHPGDKMT2AMEN1 | |
| SCHEMBL23760189 | 0.76 | ALDH1A1 (0.44) | HSD17B10MAPTMAPK1NPSR1HPGD | |
| SCHEMBL23474650 | 0.76 | MAPT (0.41) | HSD17B10TSHRMAPTMAPK1NPSR1 | |
| SCHEMBL17451673 | 0.76 | MAPT (0.45) | HSD17B10TSHRMAPTMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |