Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760196 | 0.94 | TSPO (0.37) | L3MBTL1KDM4EATMIL1R1TSPO | |
| SCHEMBL23760195 | 0.92 | L3MBTL1 (0.41) | L3MBTL1KDM4EATMIL1R1KMT2A | |
| SCHEMBL23760127 | 0.87 | IL1R1 (0.43) | L3MBTL1KDM4EATMIL1R1KMT2A | |
| SCHEMBL22036732 | 0.81 | L3MBTL1 (0.46) | L3MBTL1KDM4EATMIL1R1TSPO | |
| SCHEMBL23760174 | 0.78 | ALDH1A1 (0.37) | L3MBTL1KDM4EATMIL1R1KMT2A | |
| SCHEMBL22035864 | 0.77 | L3MBTL1 (0.47) | L3MBTL1KDM4EATMIL1R1TSPO | |
| SCHEMBL23008374 | 0.77 | L3MBTL1 (0.47) | L3MBTL1KDM4EATMIL1R1TSPO | |
| SCHEMBL23760117 | 0.77 | IL1R1 (0.43) | L3MBTL1KDM4EATMIL1R1KMT2A | |
| SCHEMBL23008358 | 0.77 | L3MBTL1 (0.50) | L3MBTL1KDM4EATMIL1R1TSPO | |
| SCHEMBL23008169 | 0.77 | L3MBTL1 (0.50) | L3MBTL1KDM4EATMIL1R1TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |