SCHEMBL23760558

SCHEMBL23760558

CC(=O)C(C)(N)C(C)(C)N1C(=O)C=CC1=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24199813 0.81 MGLL (0.35) GSK3AGSK3BMGLL
SCHEMBL17924887 0.72 MGLL (0.38) GSK3AGSK3BMGLL
SCHEMBL17145360 0.71 MGLL (0.33) GSK3AGSK3BMGLL
SCHEMBL21999424 0.71 MGLL (0.41) GSK3AGSK3BMGLL
SCHEMBL18461453 0.71 MGLL (0.41) GSK3AGSK3BMGLL
SCHEMBL29480092 0.68 MGLL (0.35) GSK3AGSK3BMGLL
SCHEMBL11509113 0.67 MGLL (0.38) GSK3AGSK3BMGLL
SCHEMBL2037967 0.67 MGLL (0.33) GSK3AGSK3BMGLL
SCHEMBL24571415 0.67 GSK3A (0.30) GSK3AGSK3BMGLL
SCHEMBL18626109 0.67 ALDH1A1 (0.32) GSK3AGSK3BMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021160825-A1 FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS PHILOCHEM AG (CH) 2021-08-19 WO disclosed