Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.82 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.82 |
| ▸ | PGK1 | P00558 | 1/20 | 0.64 |
| ▸ | PGK2 | P07205 | 1/20 | 0.64 |
| ▸ | PDE2A | O00408 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30303132 | 1.00 | ADORA3 (0.82) | ADORA3ADORA1PGK1PGK2PDE2A | |
| SCHEMBL20724628 | 1.00 | ADORA3 (0.82) | ADORA3ADORA1PGK1PGK2PDE2A | |
| SCHEMBL8971384 | 1.00 | ADORA3 (0.82) | ADORA3ADORA1PGK1PGK2PDE2A | |
| SCHEMBL8971423 | 1.00 | ADORA3 (0.82) | ADORA3ADORA1PGK1PGK2PDE2A | |
| SCHEMBL6758941 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1PGK1PGK2ADORA2A | |
| SCHEMBL4803033 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1PGK1PGK2ADORA2A | |
| SCHEMBL14853634 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1PGK1PGK2ADORA2A | |
| SCHEMBL14928752 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1PGK1PGK2ADORA2A | |
| SCHEMBL18464461 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1PGK1PGK2ADORA2A | |
| SCHEMBL5879766 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1PGK1PGK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512863-B1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2021-12-08 | — | — | EP | disclosed |
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |