SCHEMBL5879766

SCHEMBL5879766

CNc1nc(N)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 7/20 1.00
ADORA1 P30542 7/20 1.00
PGK1 P00558 1/20 0.77
PGK2 P07205 1/20 0.77
CYP2C19 P33261 2/20 0.71
ADORA2B P29275 3/20 0.67
SLC29A1 Q99808 3/20 0.67
ADORA2A P29274 2/20 0.65
HTR2A P28223 1/20 0.64
CYP1A2 P05177 1/20 0.64
CYP2D6 P10635 1/20 0.64
CYP2C9 P11712 1/20 0.64
MAPK1 P28482 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6758941 1.00 ADORA3 (1.00) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL4803033 1.00 ADORA3 (1.00) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL27578766 1.00 ADORA3 (1.00) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL14853634 1.00 ADORA3 (1.00) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL18464461 1.00 ADORA3 (1.00) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL14928752 1.00 ADORA3 (1.00) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL21276447 0.92 ADORA3 (0.86) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL22224967 0.91 ADORA3 (0.84) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL23760829 0.90 ADORA3 (0.82) ADORA3ADORA1PGK1PGK2CYP2C19
SCHEMBL20724628 0.90 ADORA3 (0.82) ADORA3ADORA1PGK1PGK2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS TRILINK BIOTECHNOLOGIES, LLC 2025-06-26 US claimed
EP-4499824-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2025-02-05 EP claimed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN claimed
WO-2023183569-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2023-09-28 WO claimed
US-20220306678-A1 IMPROVED IN VITRO TRANSCRIPTION PURIFICATION PLATFORM ARCTURUS THERAPEUTICS, INC. 2022-09-29 US claimed
US-20040110718-A1 Anti-HCV nucleoside derivatives DEVOS RENE (GB) 2004-06-10 US claimed
CN-1466591-A Nucleoside derivatives - 2004-01-07 CN claimed
WO-2002018404-A9 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C HOFFMANN LA ROCHE (CH) 2003-10-02 WO claimed
EP-1315736-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2003-06-04 EP claimed
US-20030008841-A1 Anti-HCV nucleoside derivatives F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) 2003-01-09 US claimed
WO-2002018404-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2002-03-07 WO claimed
US-20250382584-A1 CELL Tanabe, Koji (US) 2025-12-18 US disclosed
EP-4580609-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2025-07-09 EP disclosed
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS TRILINK BIOTECHNOLOGIES, LLC 2025-06-26 US disclosed
WO-2025104494-A2 COMPOSITIONS AND METHODS FOR MODULATING PROTEIN INTERACTIONS VERSAMEB AG (CH) 2025-05-22 WO disclosed
CN-1466591-A Nucleoside derivatives - 2004-01-07 CN disclosed
WO-2002018404-A9 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C HOFFMANN LA ROCHE (CH) 2003-10-02 WO disclosed
EP-1315736-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2003-06-04 EP disclosed
US-20030008841-A1 Anti-HCV nucleoside derivatives F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) 2003-01-09 US disclosed
WO-2002018404-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2002-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008841-A1 Anti-HCV nucleoside derivatives PNP, HAVCR2, NUDT14 ADORA3 102/4885ADORA1 197/4885PGK1 1287/4885
US-20040110718-A1 Anti-HCV nucleoside derivatives PNP, HAVCR2, NUDT14 ADORA3 102/4885ADORA1 197/4885PGK1 1287/4885
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS RNGTT, POLRMT, POLN ADORA3 1331/4885ADORA1 2763/4885PGK1 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.