Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 8/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.38 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760882 | 0.94 | NT5E (0.45) | NT5ERNASELP2RY1P2RY11 | |
| SCHEMBL23760747 | 0.93 | NT5E (0.44) | NT5ERNASELP2RY1P2RY11 | |
| SCHEMBL23760890 | 0.92 | CA5A (0.42) | NT5ECA5ARNASELP2RY1DNPH1 | |
| SCHEMBL23760891 | 0.92 | CA5A (0.42) | NT5ECA5ARNASELP2RY1DNPH1 | |
| SCHEMBL23760841 | 0.88 | NT5E (0.49) | NT5ECA5ARNASELP2RY1DNPH1 | |
| SCHEMBL23760912 | 0.88 | NT5E (0.50) | NT5ECA5ARNASELP2RY1DNPH1 | |
| SCHEMBL23761055 | 0.87 | CYP2C19 (0.39) | NT5EADORA1PDE4D | |
| SCHEMBL23760867 | 0.83 | P2RY1 (0.53) | NT5EP2RY1ADORA1 | |
| SCHEMBL23760905 | 0.83 | NT5E (0.46) | NT5ECA5AP2RY1 | |
| SCHEMBL23760862 | 0.83 | ABCB1 (0.49) | NT5EADORA1PDE4DTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512863-B1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2021-12-08 | — | — | EP | disclosed |
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |