Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 5/20 | 0.42 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760891 | 1.00 | CA5A (0.42) | CA5ANT5ERNASELP2RY1DNPH1 | |
| SCHEMBL23760923 | 0.92 | NT5E (0.47) | CA5ANT5ERNASELP2RY1DNPH1 | |
| SCHEMBL23760867 | 0.86 | P2RY1 (0.53) | NT5EP2RY1ADORA1 | |
| SCHEMBL23760882 | 0.86 | NT5E (0.45) | NT5ERNASELP2RY1P2RY11P2RX3 | |
| SCHEMBL23760747 | 0.85 | NT5E (0.44) | NT5ERNASELP2RY1P2RY11IMPDH2 | |
| SCHEMBL24081953 | 0.84 | NT5E (0.35) | NT5ERNASELP2RY1P2RY11IMPDH2 | |
| SCHEMBL23760862 | 0.84 | ABCB1 (0.49) | NT5EADORA1PDE4DTAS1R3TAS1R1 | |
| SCHEMBL23761017 | 0.84 | NT5E (0.34) | NT5E | |
| SCHEMBL24081958 | 0.82 | CA5A (0.54) | CA5ANT5ERNASELP2RY1DNPH1 | |
| SCHEMBL23760838 | 0.81 | NT5E (0.54) | NT5EP2RY2TAS1R3TAS1R1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |