Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760862 | 0.91 | ABCB1 (0.49) | ADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL23760814 | 0.86 | ADORA3 (0.60) | ADORA3ADORA1ADORA2B | |
| SCHEMBL23760890 | 0.86 | CA5A (0.42) | P2RY1ADORA1NT5E | |
| SCHEMBL23760891 | 0.86 | CA5A (0.42) | P2RY1ADORA1NT5E | |
| SCHEMBL23760876 | 0.84 | POLB (0.53) | ADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL23760804 | 0.84 | ADORA3 (0.42) | P2RY1ADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL23760923 | 0.83 | NT5E (0.47) | P2RY1ADORA1NT5E | |
| SCHEMBL23760838 | 0.81 | NT5E (0.54) | NT5E | |
| SCHEMBL26226278 | 0.80 | ADORA3 (0.39) | P2RY1ADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL23760836 | 0.80 | ABCB1 (0.51) | ADORA3ADORA1ADORA2BNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512863-B1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2021-12-08 | — | — | EP | disclosed |
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |