Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PDE6D | O43924 | 2/20 | 0.31 |
| ▸ | PDE6A | P16499 | 2/20 | 0.31 |
| ▸ | PDE6G | P18545 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE6B | P35913 | 2/20 | 0.31 |
| ▸ | PDE6C | P51160 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763565 | 0.85 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL23763603 | 0.82 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL23763476 | 0.81 | SRC (0.34) | FLT3HRH4PDE2APDE6DPDE6A | |
| SCHEMBL23763743 | 0.78 | HTR1D (0.32) | HRH4 | |
| SCHEMBL23763584 | 0.76 | MAPT (0.39) | FLT3MAPTKDM4EGAAMEN1 | |
| SCHEMBL24601592 | 0.75 | CYP1A2 (0.38) | CRHR1CYP1A2CYP2A6FLT3MAPT | |
| SCHEMBL23763473 | 0.72 | GABRP (0.33) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL24601506 | 0.72 | FLT3 (0.35) | CRHR1CYP1A2CYP2A6FLT3MAPT | |
| SCHEMBL25880372 | 0.72 | CYP1A2 (0.40) | CRHR1CYP1A2CYP2A6MAPTKDM4E | |
| SCHEMBL23763393 | 0.71 | MAPT (0.40) | FLT3MAPTKDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865486-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-08-18 | — | — | EP | disclosed |