Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763593 | 0.88 | TNKS (0.34) | TNKSTNKS2MAPTKIF11APEX1 | |
| SCHEMBL23763572 | 0.86 | TNKS (0.34) | TNKSTNKS2KIF11APEX1PGR | |
| SCHEMBL23763592 | 0.81 | TNF (0.33) | TNKSTNKS2KIF11APEX1PGR | |
| SCHEMBL23763745 | 0.81 | TNF (0.33) | TNKSTNKS2KIF11APEX1PGR | |
| SCHEMBL23763561 | 0.78 | PGR (0.30) | PGRRORARORCRORB | |
| SCHEMBL23763591 | 0.78 | TNF (0.32) | TNKSTNKS2KIF11PGRRORA | |
| SCHEMBL23763588 | 0.77 | PIK3CD (0.32) | MAPTKIF11PGRRORARORC | |
| SCHEMBL23763736 | 0.76 | PIK3CD (0.33) | MAPTKIF11PGRRORARORC | |
| SCHEMBL23763732 | 0.75 | HTR1D (0.31) | — | |
| SCHEMBL25682452 | 0.75 | KIF11 (0.40) | TNKSTNKS2MAPTKIF11APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865486-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-08-18 | — | — | EP | disclosed |